Hippocampal information topology breaks down in a mouse model of Alzheimer's disease
Hippocampal spatial coding depends on coordination among neuronal assemblies, yet how network topology organises information processing across these assemblies, and how this is disrupted in disease, remain unknown. We apply Partial Information Decomposition to CA1 calcium imaging from young and aged wild-type and 5xFAD mice, quantifying redundant and synergistic information sharing within and…
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