Cardinals vs Reds Prediction: Odds, recent stats, trends, and best bets for August 19

The St. Louis Cardinals and Cincinnati Reds are set to face off in the fourth game of their five-game series on Wednesday, August 19, 2026, at Great American Ball Park in Cincinnati, OH. The Cardinals are currently 65-62, while the Reds sit at 60-66. Over their last five games, the Reds have struggled, going 1-4, while the Cardinals have been strong, posting a 4-1 record in the same span.

Cincinnati is 3.0 games behind the final in the NL Wild Card race, trailing the Cubs, Phillies, Padres, and Diamondbacks. The Cardinals' pitching rotation is second in ERA (2.94), fifth in WHIP (1.18), and fourth in OBA (.224). However, the Reds' pitching staff is having a tough time, with a 22nd-ranked ERA (4.53) in August and a dead-last batting average of .193.

Chase Burns will take the mound for Cincinnati, with a 14-2 record and a 2.47 ERA, while the Cardinals' Matthew Liberatore has a 5-10 record, 5.07 ERA, and 1.48 WHIP.