Astrocyte-Selective Wireless Deep Brain Stimulation by Magnetite Nanodiscs at Low Alternating Magnetic Field

Astrocytes are essential regulators of synaptic transmission, brain homeostasis and behavior, and direct astrocyte activation has emerged as a promising therapeutic modality for a broad range of CNS disorders. However, selective activation of astrocytes in vivo currently requires viral transgene delivery, tethered fiber implants, or MRI-scale magnetic fields, limiting deployment across…

biorxiv.org ·19h ago

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