Architectures and biochemical activities of Mtl1-Red1 MTREC helicase complexes
RNA surveillance and decay is carried out in part by helicase containing complexes that identify, capture and sometimes modify RNA before delivering it to the RNA exosome complex for processing or degradation. The MTREC core complex includes a Mtr4-like protein (Mtl1) helicase and Red1 that works with other cofactors and the RNA exosome in Schizosaccharomyces pombe to degrade nuclear transcripts…
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