AlphaVaR: an R framework for the statistical interpretation of AlphaGenome variant-effect predictions

AlphaGenome (Google DeepMind) scores a DNA variant across thousands of functional tracks at single-base resolution, reporting both the magnitude of each predicted effect and its rarity against a genome-wide background. That volume is itself the obstacle to biological interpretation. Here we present AlphaVaR, an R package that gives AlphaGenome's output a typed structure together with the…

biorxiv.org ·22h ago

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