Single-cell profiling identifies STAT3/NF-κB regulatory hubs and cytokine crosstalk in the tumor microenvironment
Tumor progression is driven by dynamic interactions between malignant cells and the tumor microenvironment (TME), yet the regulatory mechanisms governing cellular heterogeneity and intercellular communication remain incompletely characterized. Here, we performed integrative single-cell RNA sequencing (scRNA-seq) analysis of publicly available datasets from non-small cell lung cancer and breast…
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