NFL players whose Week 1 status is in question

As the NFL season approaches, several players are facing uncertainties regarding their availability for Week 1. Alec Pierce of the Indianapolis Colts is recovering from ankle surgery but is expected to be ready for the season opener. New York Jets running back Breece Hall missed practice due to a groin injury but is likely to play against Tennessee.

San Francisco 49ers Christian McCaffrey is dealing with muscle tightness, which could affect his Week 1 status. Arizona Cardinals rookie running back Jeremiyah Love suffered a high ankle sprain against the Las Vegas Raiders, and his Week 1 status is uncertain. Green Bay Packers Josh Jacobs may miss several weeks due to an arrest in May, but charges were dropped, and the NFL may still discipline him.

Chicago Bears running back Kyle Monangai injured his knee during a training camp drill, and his Week 1 availability is unclear. Chicago Bears safety Luther Burden III is expected to miss 3-4 weeks due to a groin injury. New York Giants wide receiver Malik Nabers, who recently recovered from a serious ACL and meniscus tear, is on track to play Week 1.

Kansas City Chiefs quarterback Patrick Mahomes, recovering from a torn ACL suffered in Week 15 of the 2025 season, was cleared for training camp and is expected to start the season opener against the Denver Broncos. Los Angeles Rams receiver Puka Nacua may face a Week 1 suspension due to his offseason antics, including antisemitic comments and a civil lawsuit from a New Year's Eve incident.