Heat-not-burn tobacco, e-cigarettes may be linked to postoperative recurrence of Crohn's disease
For patients with Crohn's disease (CD), heat-not-burn tobacco (HNBT) and possibly electronic cigarette (e-cigarette) use are associated with increased postoperative endoscopic recurrence of CD, according to a study published in the August issue of the American Journal of Gastroenterology.
Patients with Crohn's disease who use heat-not-burn tobacco (HNBT) or e-cigarettes face a higher risk of postoperative endoscopic recurrence compared to those who do not use these products, according to a study published in the American Journal of Gastroenterology. Researchers from IRCCS Ospedale San Raffaele in Milan conducted a multicenter international study, analyzing data from 937 patients who underwent ileocolic resection for Crohn's disease and had their endoscopy within a year.
The study found that conventional cigarette smokers had the highest recurrence rate (69.4%), followed by HNBT users (63.9%) and e-cigarette users (60.6%). Nonsmokers had a lower recurrence rate (40.8%). After adjusting for various factors, HNBT use remained significantly associated with recurrence, while the e-cigarette association was not statistically significant.
The researchers suggest that patients with Crohn's disease using HNBT or e-cigarettes be managed similarly to traditional smokers in the postoperative setting.
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