Autoinjectable PCSK9 Inhibitor; Caution on CoQ10; Ohio Doc's Rape Charges

The FDA approved an autoinjector version of lerodalcibep, a PCSK9 inhibitor for lowering LDL cholesterol, announced LIB Therapeutics. Bracco Imaging received FDA clearance for its VueJect contrast delivery system to be used with cardiac ultrasounds. However, Philips issued a recall of over 2,600 Cardiac Workstation systems due to a software issue causing inaccurate heart rate readings. The devices can still be used, but with manual corrections.

Cardiologists caution against marketing claims promoting CoQ10 supplements. Actress Hayden Panettiere reportedly suffered cardiac arrest before dying at age 36. Bempedoic acid, or Nexletol, reduced cardiovascular and limb events in patients with peripheral artery disease in the CLEAR Outcomes trial.

A survey found that "statin-intolerant" people were more wary of medication and healthcare professionals in general. Serial cardiac MRI findings supported the use of vutrisiran (Amvuttra) for patients with transthyretin amyloid cardiomyopathy, according to the HELIOS-B trial. An AI-based ECG analyzer trained for structural heart disease detection performed less effectively in a community-based cohort.

A registry study did not find a link between pre-existing structural heart disease and post-COVID-19 complications. A draft report from the Institute for Clinical and Economic Review found aldosterone synthase inhibitors baxdrostat and lorundrostat only promising for hypertension compared to other medications like spironolactone, eplerenone, or amiloride.

In Sweden, people with atrial fibrillation and Alzheimer's disease taking direct oral anticoagulants showed slower cognitive decline and better efficacy-safety balance compared to warfarin or no anticoagulation. Ultrasound imaging via electromechanical wave analysis was introduced to map arrhythmogenic risks in mitral valve disease. Outpatient lung impedance-guided therapy showed promise for heart failure with preserved ejection fraction.

A cardiologist in Ohio had his medical license suspended by the state medical board after being arrested for allegedly raping and sexually battering patients.