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Molecular arms race in WHO elements, a category of homing genetic elements distinct from inteins and introns

Homing genetic elements are selfish elements that insert themselves into a specific site in a host gene without disrupting its function. They spread through the population because the element codes for an endonuclease that cleaves alleles of the host gene that do not contain the element, leading to DNA repair by gene conversion that increases the element's frequency. Most homing genetic elements…

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