Higher-Order Mechanical Neighbourhood Sensing Governs Cell Fate in Complex Tissues
Adult tissues maintain precise architectures composed of multiple interspersed cell types, yet prevailing models of cell fate patterning rely on pairwise interactions between neighbouring cells that generate binary decisions. How local interactions encode higher-order, beyond pairwise, multicellular organization remains unclear. Here, using the Drosophila midgut as a model of adult tissue…
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