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Autonomous Spatial Transcriptomics Analysis (ASTA): Demonstrating Performance Improvements through Clustering, Biological Annotation, and AI-Driven Discovery

Spatial transcriptomics keeps measurement of gene expression while preserving spatial context, yet traditional analysis methods face challenges in computational efficiency, biological interpretability, and autonomous discovery. This project presents a framework solving these issues through three parts: (1) an ensemble clustering system achieving 66.7% improvement over baseline average and 23.9%…

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