Tissue-resident memory B cells augment local anti-cancer immunity via IgA
Tissue-resident memory B cells (BRM) provide powerful localized protection against microbial infection in barrier tissues. It is unknown if analogous BRM populations survey solid tumors and contribute to anti-cancer immunity. We profiled B cells from patients with colorectal cancer and cutaneous basal cell carcinoma and identified a CD69 memory B cell population consistent with a tissue-resident…
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