Single-cell analyses reveal a simple multi-gene transcriptomic signature with predictive power in prognosis and therapy effectiveness in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive, heterogeneous form of breast cancer with limited specific therapy options, prevalent metastasis and frequent relapse. Re-analysis of single-cell RNA-sequencing data characterizes the diverse cell subtypes within the tumor and microenvironment of TNBC, supporting a luminal progenitor origin for the cancer and providing clues as to the factors…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
