Rb's unexpected activation of estrogen-responsive genes could explain breast cancer treatment resistance
Researchers at Peter Mac have discovered why breast cancer treatment stops working for some patients, uncovering the unexpected role of one of the body's most important cancer-fighting proteins. The study, published in Nature, revealed that the retinoblastoma (Rb) protein—long considered one of the body's natural brakes on cancer growth—has a more complex function than previously understood.
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