Preoperative GLP-1s Don't Diminish Bariatric Surgery Results, Study Suggests
(MedPage Today) -- Bariatric surgery patients who took GLP-1 medications prior to surgery lost the same amount of weight after 1 year as individuals unexposed to the blockbuster class of drugs, a retrospective review indicated. Among 383 patients...
A recent study indicates that taking GLP-1 medications prior to bariatric surgery does not reduce the effectiveness of the surgery, according to a review of patient outcomes. Among 383 patients who underwent the procedure, those who had taken a GLP-1 drug beforehand lost the same amount of weight as those who had not - 24% of their total body weight within a year.
The average weight loss was also similar, at 66 pounds (30 kilograms) for both groups (P=0.33). No differences were found in diabetes control or complication rates between the two groups. The researchers were surprised by these findings, as they had expected preoperative GLP-1 use to interfere with surgical weight loss. However, the study suggests that patients can still achieve significant weight loss and diabetes management benefits from both medicine and surgery. Further research is needed to determine the optimal sequence and combination of obesity treatments.
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