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Stopping Statins in Trial Didn't Raise Mortality Risk, but ...

(MedPage Today) -- Experts were still unsure whether stopping primary prevention statins in the elderly was a good idea following the report of a modestly sized randomized trial. In Statins in the Elderly (SITE, also known as SAGA), statin discontinuation...

Stopping Statins in Trial Didn't Raise Mortality Risk, but ...

A recently completed clinical trial has found that stopping primary prevention statins in elderly patients did not increase mortality risk. Known as the Stopping Statins in the Elderly (SITE, or SAGA), the study of over 1,000 people ages 75 and older with long-term statin use and no history of atherosclerotic cardiovascular disease found no difference in death rates between those who continued their medication and those who stopped it.

However, the trial did not provide clear evidence on whether stopping statins offers any tangible benefits to patients who have been on the therapy for a long time with no issues. Researchers suggest this data should prompt a shared decision-making conversation between patients and doctors when determining the best course of action for statin use in the elderly.

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