Plasmid biology is compressed in host chromosomal architecture
Plasmids drive horizontal gene transfer and the spread of antibiotic resistance, yet their distribution across microbial genomes is highly uneven and often viewed as environmentally driven, leaving unresolved whether host chromosomal architecture imposes predictable constraints. Here, using machine learning on 52,393 complete prokaryotic genomes, we show that chromosomal gene content encodes…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
