Quantification of bone loss, periosteal bone formation and novel histopathological changes in a mouse implant-related Staphylococcus aureus infection model
Implant-associated bone infection involves a complex interplay between pathogenic stimuli and host cell responses, yet analysis in preclinical models has typically relied on qualitative or semi-quantitative measures. We aimed to establish a quantified evaluation framework to define host-pathogen relationships in a preclinical implant infection model. Staphylococcus aureus-coated stainless-steel…
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