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White-matter functional connectivity uniquely predicts brain age, cognition, and psychopathology beyond gray-matter connectivity

Proceedings of the National Academy of Sciences, Volume 123, Issue 34, August 2026. SignificanceAlthough functional signals have been detected in human white matter (WM), whether functional connectivity (FC) involving WM contributes information beyond gray-matter FC remains unclear. Across multiple independent cohorts, we show that white-...

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