Presynaptic mechanism of epileptiform activities in forward-programmed human excitatory neuronal networks
Epilepsy is one of the most common neurological disorders, yet the mechanisms controlling seizure termination remain poorly understood. In particular, why rhythmic spike-wave discharges decelerate before stopping is unexplained. Here, using human iPSC-derived excitatory neurons differentiated via targeted forward-programming, we report a similar deceleration phenomenon in cultured neuronal…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
