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Major earthquake of magnitude 7.4 shakes Colombia, neighbouring Ecuador, Venezuela

The Colombian geological service reported that the quake's epicentre was in Choco province, on the Pacific coast.

Major earthquake of magnitude 7.4 shakes Colombia, neighbouring Ecuador, Venezuela

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New GLP-1 pill delivers up to 12% weight loss in 36 weeks

An experimental GLP-1 pill helped people with obesity or overweight lose as much as 12.1% of their body weight in just 36 weeks. Unlike injectable drugs such as Wegovy and Ozempic, aleniglipron is a small molecule that can be taken once daily with or without food and could potentially be produced more easily at scale.

  • Aleniglipron oral GLP-1 treatment helps adults lose up to 12% body weight in 36 weeks
  • Developed by Structure Therapeutics, aleniglipron is small-molecule drug vs injectable GLP-1 drugs
  • Phase II trial with 230 participants showed average 9.0% weight loss in lowest dose group