Immunomodulatory mechanisms of submicron phosphatidylserine-exposing polymeric particles (PSPs)
Macrophages are highly dynamic cells that maintain tissue homeostasis by regulating both initiation and resolution of inflammation. During efferocytosis, macrophages recognize the 'eat me' signal, phosphatidylserine (PS), exposed at the surface of apoptotic cells, leading to the resolution of inflammation and acquisition of a pro-resolving phenotype. Inspired by this endogenous mechanism,…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
