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Assessing Computational Models for Pharmacogenomic Variant Interpretation

Accurately predicting the effects of pharmacogenomic variants is essential for the development of personalized therapeutic strategies, as genetic variability can influence drug response differently across patients. Here, we assessed several computational approaches using a dataset of pharmacogenomic variants with either clinical annotations or functional characterization by deep mutational…

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Fauci Text Reveal: What It Shows About COVID Vaccine Risk to Pregnant Women

Newly released Fauci texts show how top health officials weighed pregnancy risks and limited vaccine data in early 2021.

  • Text messages reveal Fauci's 2021 discussions on COVID vaccine risks for pregnant women.
  • Officials acknowledged theoretical miscarriage risk in early pregnancy but found no safety problems.
  • CDC established pregnancy registry to monitor outcomes after initial data collection.