How weight-loss medication is changing relationships with alcohol

Lisa Rees, a 46-year-old woman from South Wales, started taking the weight-loss medication Wegovy in April. She never anticipated that one of the drug's side effects would be a significant reduction in her alcohol consumption. Previously, Lisa would consume two bottles of wine during a night out, but now, after just a few glasses, she finds it physically impossible to drink more.

This change in her relationship with alcohol has been a positive outcome for Lisa, who no longer worries about the health risks associated with excessive drinking. Early research suggests that weight-loss drugs containing semaglutide or tirzepatide may reduce cravings for substances such as alcohol and nicotine by affecting the brain's reward response.

While some people report no change in their alcohol consumption while on these medications, others experience a significant decrease. Researchers and medical professionals emphasize that people on weight-loss drugs should be mindful of their alcohol intake, as these medications can lead to reduced appetite and increased fullness, which may naturally discourage alcohol consumption.

However, for some individuals, such as Faye Goodwin, a 20-year-old recent graduate, the medication has negatively impacted her social life and ability to enjoy alcohol without experiencing nausea or discomfort. The effects of weight-loss drugs on alcohol consumption remain an area of ongoing research, with data accumulating rapidly.