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Less Protein, Not More, May Lead to Healthier Aging

A new review takes a closer look at the molecular mechanisms The post Less Protein, Not More, May Lead to Healthier Aging appeared first on Nautilus .

Less Protein, Not More, May Lead to Healthier Aging

A new review in the journal Cell Press Blue suggests that reducing protein intake may lead to healthier aging, contrary to recent federal dietary guidelines that recommend higher protein consumption. The researchers from the University of Wisconsin-Madison analyzed over 350 studies involving the effects of a protein-restrictive diet on various organisms.

They found that decreasing protein intake is linked to improved metabolism, reduced cellular damage, and healthier aging. A key factor in this process is a hormone called fibroblast growth factor 21 (FGF21), which increases when protein intake decreases. FGF21 can boost energy expenditure, stabilize blood sugar levels, and reduce inflammation, potentially leading to a longer lifespan in mice.

The researchers also discovered that consuming certain essential amino acids can exacerbate age-related maladies like obesity and inflammation. According to the study authors, the current high protein intake may have negative health consequences for sedentary individuals, and personalized protein recommendations based on physical activity levels may be necessary.

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