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PHOTORELEASE OF OXYTOCIN IN VIVO USING PHOTOSWITCHABLE NANOVESICLES MODULATES HIPPOCAMPAL CIRCUIT DYNAMICS AND SOCIAL BEHAVIOR

Achieving precise spatiotemporal control over neuropeptide delivery in vivo remains a major challenge, as conventional approaches lack temporal resolution and control over release kinetics or have limitations for in vivo applications. Here, we demonstrate that photoswitchable azobenzene-containing lipid nanovesicles (azosomes) enable light-controlled release of neuropeptides in vivo in the brain…

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