LIPOGRID: A HIGH-THROUGHPUT MULTI-OMICS PERTURBATION SCREEN DISSECTS THE GENETIC ARCHITECTURE OF LIPID METABOLISM
Lipids constitute one of the largest and most diverse classes of cellular molecules, sustaining membrane architecture, energy storage, and signaling. Consequently, their dysregulation underlies a broad spectrum of human disease. However, the genetic mechanisms governing lipid homeostasis have remained largely inaccessible, owing to the lack of approaches capable of systematically linking defined…
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