IsoMobil: Resolving Molecular Ambiguity in Mass Spectrometry-based Spatial Omics Through Ion Mobility
Molecular imaging by imaging mass spectrometry (IMS) has become a key modality for spatial proteomics, lipidomics, glycomics, and metabolomics. It maps hundreds to thousands of molecular species con-currently throughout tissue without prior labeling. However, reporting thousands of ion images makes IMS measurements very high-dimensional, complicating interpretation. Furthermore, IMS data contain…
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