Re-evaluating Reported Pseudolysogeny in Phage T3: T3 and T7 Show Similar Propagation Responses to Nutrient Limitation and Media Switching
Pseudolysogeny is a latent state in which phage development is delayed after infection and has been proposed to promote phage persistence under unfavorable conditions. Virulent phage T3 has been reported to establish pseudolysogeny after infecting starved E. coli, then resume lytic replication following transfer to nutrient-rich media, a phenotype linked to the T3 SAMase gene. Here, we revisited…
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