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Virtual spatial transcriptomics from histopathology enables prognostic and therapeutic response prediction in cancer

Spatial transcriptomics reveals cellular heterogeneity, intercellular communication, and tissue organization, but its cost and limited accessibility restrict clinical use. Here, we present VISTA, a model that integrates multi-scale histological features and spatial context to infer spatial gene expression from H&E stained tissue images. Across leave one section out cross validation and…

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Fauci Text Reveal: What It Shows About COVID Vaccine Risk to Pregnant Women

Newly released Fauci texts show how top health officials weighed pregnancy risks and limited vaccine data in early 2021.

  • Text messages reveal Fauci's 2021 discussions on COVID vaccine risks for pregnant women.
  • Officials acknowledged theoretical miscarriage risk in early pregnancy but found no safety problems.
  • CDC established pregnancy registry to monitor outcomes after initial data collection.