pbcftools: parallel execution of bcftools for large variant call sets
Summary bcftools is the standard toolkit for handling VCF and BCF variant files, but it processes records on a single core; its --threads option speeds up only compression of the output, not the work done on variant records. Processing large call sets is therefore slow, and users often divide the genome and reassemble the results by hand. We present pbcftools, a Perl wrapper that does this…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
