Move BeTween modAlities (MBTA) employs flow matching to predict single cell data modalities
Integrating diverse molecular modalities to obtain a comprehensive view of cellular identity remains a major challenge in single-cell biology. A fundamental but underappreciated obstacle is structural mismatch-the phenomenon in which the neighborhood structure of a cell differs depending on which molecular modality is used to define it. Existing approaches typically embed modalities into a shared…
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