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BUsmear: A Low-Cost 3D-Printed Automated Device for Blood Smear Preparation

Uniform, reproducible blood smears are critical for reliable hematological evaluation. Manual smear preparation, however, is user-dependent and introduces variability that limits quantitative microscopy. Here we developed BUsmear, a low-cost, 3D-printed, motorized blood smear device that prepares two smears simultaneously from a printed stage and a micro-motor drive with tunable linear velocity,…

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Transcriptome, glycome, and mucinome analysis reveal zinc is essential for the composition of mucus in the human goblet cell model HT-29-MTX

Scientific Reports, Published online: 11 August 2026; doi:10.1038/s41598-026-66227-4 Transcriptome, glycome, and mucinome analysis reveal zinc is essential for the composition of mucus in the human…

  • Zinc deficiency impacts 1 billion globally, causing health issues
  • Zn deficiency alters HT-29-MTX GC transcriptome and mucin synthesis
  • MUC2 and MUC17 levels increase, complex N-glycans decrease in Zn-deficient GCs