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ABC1K7: A 350-Myr chloroplast rheostat fine-tuned during coconut domestication

Perennial crops follow different domestication trajectories from annuals, yet the molecular basis of slow-variable domestication - subtle tuning of conserved regulatory hubs - remains poorly characterized. We reconstructed the evolutionary history of the chloroplast kinase ABC1K7 across 9 seed plant species spanning ~350 Myr, employing PAML codon models, IQ-TREE robust codon models, and…

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Transcriptome, glycome, and mucinome analysis reveal zinc is essential for the composition of mucus in the human goblet cell model HT-29-MTX

Scientific Reports, Published online: 11 August 2026; doi:10.1038/s41598-026-66227-4 Transcriptome, glycome, and mucinome analysis reveal zinc is essential for the composition of mucus in the human…

  • Zinc deficiency impacts 1 billion globally, causing health issues
  • Zn deficiency alters HT-29-MTX GC transcriptome and mucin synthesis
  • MUC2 and MUC17 levels increase, complex N-glycans decrease in Zn-deficient GCs