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Dual control of PIP2 drives germline/soma segregation in Drosophila

Proceedings of the National Academy of Sciences, Volume 123, Issue 31, August 2026. SignificanceIn animal embryos, primordial germ cells (PGCs) and endoderm arise in proximity. InDrosophila, the separation between the two cell types occurs at the posterior pole of the embryo while it is a syncytium. The cues that designate PGCs and ...

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