{
  "id": 9754024,
  "title": "APOA1 links a late fetal epithelial program to colonic maturation and injury responses",
  "url": "https://urgent.news/2026/09/25/apoa1-links-a-late-fetal-epithelial-program-to-colonic-maturation-and",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-25T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.24.754040v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Developmental programs establish tissue identity and organization, but how their reactivation contributes to adult tissue responses remains poorly understood. Here, we identify a functional contribution of apolipoprotein A-I (APOA1), which marks a late fetal colonic epithelial state that reappears after injury. Spatial and temporal profiling localized Apoa1 transcription predominantly to…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}