{
  "id": 9357172,
  "title": "PROXINAUT: An Automation Platform for Rapid Hit-to-Degrader Discovery",
  "url": "https://urgent.news/2026/09/23/proxinaut-an-automation-platform-for-rapid-hit-to-degrader-discovery",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-23T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.22.753586v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Massive library-based platforms enable rapid early hit discovery, yet subsequent hit resynthesis and validation remain major bottlenecks in drug discovery. This delay is amplified when optimizing hits, or elaborating structures towards more advanced modalities, such as chemical inducers of proximity (CIPs). Here, we report PROXINAUT, an end-to-end workflow integrating self-encoded library-based…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}