{
  "id": 9228265,
  "title": "Evaluations of retrospective frequency and phase correction methods for single-voxel MR spectroscopy at 7T",
  "url": "https://urgent.news/2026/09/22/evaluations-of-retrospective-frequency-and-phase-correction-methods",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-22T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.21.753210v1?rss=1"
  },
  "original_language": "en",
  "account": "Single-voxel MR spectroscopy (SVS) acquisitions are affected by subject motion and gradient heating, leading to spectral misalignment. Researchers evaluated four retrospective correction methods for SVS data at a 7T system, namely creatine fitting, residual water, spectral registration, and cross-correlation. The study included 127 participants (88 female and 39 male, with an average age of 39±15 years) using a semi-localization by adiabatic selective refocusing sequence. After correction, changes in spectral linewidth, signal-to-noise ratio (SNR), similarity (mean similarity matrix (SImean)), and metabolite quantification (concentration and relative Cramer-Rao lower bounds (rCRLB)) were assessed. A Wilcoxon signed rank test was used to compare these changes, with p-values adjusted using the false discovery rate (q 0.60). The results showed that the correction had a weak to moderate effect on metabolite quantification, with an effect size not specified in the source material.",
  "summary": "Subject motion and gradient heating-induced frequency and phase offsets result in spectral misalignment during single-voxel MR spectroscopy (SVS) acquisitions. Several methods have been presented to align the spectra, but their performance on a 7T system is unclear. This study aimed to evaluate the practical importance of four retrospective correction methods, namely creatine fitting, residual…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}