{
  "id": 920570,
  "title": "PACE, Proximity-Associated Changes in Expression",
  "url": "https://urgent.news/2026/08/14/pace-proximity-associated-changes-in-expression",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-14T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.09.743800v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Cellular transcriptional states are shaped by local tissue context, yet quantifying how cellular gene expression varies with proximity to different cell types remains challenging. Cell-resolved spatial transcriptomics data are typically sparse and susceptible to contamination from neighbouring cells through diffusion, imperfect segmentation and cell overlap, making it difficult to distinguish…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}