{
  "id": 9153016,
  "title": "Structural basis of interaction between Pol1 and DnaN from Mycobacterium tuberculosis",
  "url": "https://urgent.news/2026/09/22/structural-basis-of-interaction-between-pol1-and-dnan-from",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-22T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.19.751633v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "DNA polymerases generally interact with the processivity clamp (DnaN/{beta}-clamp) during replication via clamp-binding motifs (CBMs). Since a CBM was not detected in DNA Polymerase I (PolI) from E. coli, it is generally believed that PolI performs its functions in genome replication and repair, independently of the {beta}-clamp. We observe that, while PolI and {beta}-clamp proteins from E. coli…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 2,
    "also_reported_by": [
      {
        "outlet": "bioRxiv",
        "title": "Variation in multiple classes of simple sequence repeats can alter drug susceptibility in Mycobacterium tuberculosis",
        "url": "https://urgent.news/2026/09/20/variation-in-multiple-classes-of-simple-sequence-repeats-can-alter",
        "published": "2026-09-20T00:00:00.000Z"
      }
    ]
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}