{
  "id": 913756,
  "title": "Systematic assessment of transcriptomic and phenotypic biologicalprofiling for mechanism-based hazard assessment using target-annotated reference chemicals in renal proximal tubular epithelialcells",
  "url": "https://urgent.news/2026/08/14/systematic-assessment-of-transcriptomic-and-phenotypic",
  "topic": "science",
  "section": "Science",
  "published": "2026-08-14T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.08.08.743660v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Integrating high-throughput in vitro data into next-generation risk assessment (NGRA) workflows requires screening strategies that yield quantitative potency estimates and mechanistically interpretable biological signals. Transcriptomic and morphological profiling are increasingly adopted for early-stage hazard identification by enabling triage of substances for resource-intensive follow-up and…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}