{
  "id": 9072980,
  "title": "Maleic acid adjuvates BCG to induce CD4+CD8+ T cells and sterilize tuberculosis",
  "url": "https://urgent.news/2026/09/21/maleic-acid-adjuvates-bcg-to-induce-cd4-cd8-t-cells-and-sterilize",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-21T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.20.752978v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Anti-tuberculosis (TB) immunity typically emphasizes CD4+ T and CD8+ T cells that only provide limited protection against Mycobacterium tuberculosis (Mtb) infection. The anti-TB function of CD4+CD8+ T cells remains unexplored, mostly due to the dogma that ThPOK and Runx3 antagonize each other to block their development and their scarcity. Here, we show that immunization of BCG (Bacillus…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}