{
  "id": 8835226,
  "title": "Structure-based Antibody Renumbering",
  "url": "https://urgent.news/2026/09/20/structure-based-antibody-renumbering",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-20T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.16.751788v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Antibody numbering schemes like IMGT and Chothia assign each residue in the variable domain a consistent index based on substructural position. These annotations standardize sequences with different lengths, facilitating tasks ranging from engineering of individual molecules during drug development to large-scale curation of training data for de novo antibody design. Yet existing algorithms for…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}