{
  "id": 8835223,
  "title": "Scaling Network Medicine with LLMs for Combinatorial Drug Repurposing in ER+ Breast Cancer",
  "url": "https://urgent.news/2026/09/20/scaling-network-medicine-with-llms-for-combinatorial-drug-repurposing",
  "topic": "ai",
  "section": "AI",
  "published": "2026-09-20T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.14.728753v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Drug repurposing can accelerate therapy discovery for ER+ breast cancer, but combination selection remains difficult. We developed an LLM-driven network medicine framework that extracts drug--target relationships from 595,122 PubMed abstracts, builds a cross-model consensus network, overlays it onto the KEGG estrogen signaling pathway, and enumerates complementary drug pairs. Candidate…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}