{
  "id": 8288606,
  "title": "Calmodulin mutation N54I causes autosomal dominant CPVT in mice",
  "url": "https://urgent.news/2026/09/18/calmodulin-mutation-n54i-causes-autosomal-dominant-cpvt-in-mice",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-18T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.12.751164v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterized by stress- or catecholamine-induced ventricular arrhythmias in the absence of overt structural heart disease. Mutations in RYR2 and CASQ2 account for most genetically defined cases, although pathogenic variants in the three genes encoding calmodulin (CALM1-3) have also been linked to…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}