{
  "id": 7839962,
  "title": "One mechanism, two diseases: Involvement of enzyme–substrate complexes in the pathogenesis of celiac disease and rheumatoid arthritis",
  "url": "https://urgent.news/2026/09/04/one-mechanism-two-diseases-involvement-of-enzyme-substrate-complexes",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-04T07:00:00.000Z",
  "source": {
    "name": "PNAS",
    "slug": "pnas",
    "url": "https://www.pnas.org/doi/abs/10.1073/pnas.2600933123?af=R"
  },
  "original_language": "en",
  "account": null,
  "summary": "Proceedings of the National Academy of Sciences, Volume 123, Issue 37, September 2026. Celiac disease (CeD) and rheumatoid arthritis (RA) share several key features. In both diseases HLA class II allotypes are the major genetic determinants, in both diseases there are antibodies to posttranslationally modified peptides (i.e., deamidated ...",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}