{
  "id": 7800612,
  "title": "A systematic interactome of <i>Saccharomyces cerevisiae</i> SET1C expands its functional landscape and identifies candidate regulatory connections",
  "url": "https://urgent.news/2026/09/16/a-systematic-interactome-of-i-saccharomyces-cerevisiae-i-set1c",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-09-16T00:00:00.000Z",
  "source": {
    "name": "eLife",
    "slug": "elife",
    "url": "https://elifesciences.org/articles/109886"
  },
  "original_language": "en",
  "account": null,
  "summary": "Set1 is the catalytic subunit of SET1C or COMPASS, which methylates histone H3K4 and serves as a scaffold for the association of seven tightly bound polypeptides. We have employed yeast two-hybrid screenings to determine the interactome of Set1 and each subunit, providing a unique resource for exploring known and novel roles of the complex. Our screenings identified a multitude of potential…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}