{
  "id": 7618086,
  "title": "Exosomes Linked to Nerve Irritation, Dysfunction, and Lingering Pain After Shingles",
  "url": "https://urgent.news/2026/09/15/exosomes-linked-to-nerve-irritation-dysfunction-and-lingering-pain",
  "topic": "health",
  "section": "Health & Medicine",
  "published": "2026-09-15T19:28:54.000Z",
  "source": {
    "name": "GEN Biotechnology",
    "slug": "gen-biotechnology",
    "url": "https://www.genengnews.com/topics/translational-medicine/exosomes-linked-to-nerve-irritation-dysfunction-and-lingering-pain-after-shingles/"
  },
  "original_language": "en",
  "account": null,
  "summary": "Researchers at the University of Colorado Anschutz have discovered that exosomes, extracellular vesicles released by cells, may be responsible for post-herpetic neuralgia (PHN) in some individuals who have had shingles. PHN is characterized by lingering pain that persists long after the varicella zoster virus (VZV) has cleared the body. The study found that exosomes released during a shingles infection can cause nerve cells to become highly active and release inflammatory signals, even without the presence of the virus. These exosomes continue to deliver damaging messages to nerves, preventing them from recovering normally and leading to a \"failure-to-resolve\" model of PHN. This new understanding of the role of exosomes in PHN may open the door to novel approaches for predicting, preventing, and treating the condition.",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}