{
  "id": 7526179,
  "title": "Asymmetric turnover dynamics of Nav1.6 voltage-gated sodium channels at the axon initial segment",
  "url": "https://urgent.news/2026/09/15/asymmetric-turnover-dynamics-of-nav1-6-voltage-gated-sodium-channels",
  "topic": "science",
  "section": "Science",
  "published": "2026-09-15T00:00:00.000Z",
  "source": {
    "name": "bioRxiv",
    "slug": "biorxiv",
    "url": "https://www.biorxiv.org/content/10.64898/2026.09.10.747750v1?rss=1"
  },
  "original_language": "en",
  "account": null,
  "summary": "Nav1.6 voltage-gated sodium channels are critical for shaping action potentials, and their precise localization at the axon initial segment (AIS) is essential for neuronal excitability. However, the turnover mechanisms that maintain this spatial pattern remain unclear. Here, we present a genetically engineered mouse in which endogenous Nav1.6 carries a Cre-switchable fluorescent tag, enabling us…",
  "key_points": [],
  "editors_take": null,
  "illustration": null,
  "coverage": {
    "outlets": 1,
    "also_reported_by": []
  },
  "ai_generated": true,
  "disclaimer": "Summaries, key points and the editor’s take are written by software from other outlets’ reporting and may contain errors — always check the linked original."
}